A breach between Earth and the netherworlds opened up over the city of New York, trapping New Yorkers and creatures from other dimensions in an impenetrable bubble. Over time, this bubble became Jerusalem's Lot, a homeworld of wondrous beings and crazy sci-fi sensibilities. Now someone is threatening to sever the bubble and unleash chaos across the dimensions, and it's up to a special group of superhumans to preserve Jerusalem's Lot.